Fat Grafting with Adipose Stem Cells: TheSuccesses and Challenges
نویسندگان
چکیده
In recent years, fat grafting has become a popular method for clinically correcting soft tissue deformities. In order to increase fat graft viability a variety of modifications have been made to current grafting procedures including cell-assisted lipotransfer (CAL), structural fat grafting, fat grafting mixed with adipose stem cells (ASCs), fat grafting mixed with platelet rich plasma (PRP) and fat grafting mixed with both ASCs and PRP; however, the persistence of the grafts after transplantation remains inconsistent. In this review, the biological fundamentals of lipotransfer procedures are discussed, the current progress of clinical fat grafting applications in plastic and reconstructive surgery is summarized, and the challenges facing fat transplantation are outlined.
منابع مشابه
Buccal fat pad: A location for obtaining adipose divide stem cells
Background Buccal fat pad is known as anatomic structure in between the masticatory muscles that separate these muscles from each other and surrounding bone. Ease of access, through the intraoral route makes it suitable choice for obtaining adipose derived stem cells. Methods Intraoral incisions for getting access to the buccal fat of pad are; Retromolar incision, incision in medial of pt...
متن کاملIsolation, Characterization and Differentiation of Rat Adipose Tissue Derived Mesenchymal Stem Cells
Introduction: Mesenchymal stem cells have the potential of self-renewal and differentiation into different cell types, including blood cells, heart, nerves and cartilage, and have unlimited power for division. These cells can be obtained from cord, before implantation from fertilized cells and also from various tissues of adults although the differentiation power and the ability to reproduce ...
متن کاملMesenchymal Stem Cells Derived from Rat Epicardial Versus Epididymal Adipose Tissue
Objective(s) Some investigation has indicated that adipose-derived stem cells possess different surface epitopes and differentiation potential according to the localization of fat pad from which the cells were derived. In the present study proliferation capacity and aging of such cells were explored. Materials and Methods Adherent cells were isolated from the collagenase digests of adipose tiss...
متن کاملApplication of adipose-derived stromal cells in fat grafting: Basic science and literature review
Autologous fat is considered the ideal material for soft-tissue augmentation in plastic and reconstructive surgery. The primary drawback of autologous fat grafting is the high resorption rate. The isolation of mesenchymal stem cells from adipose tissue inevitably led to research focusing on the study of combined transplantation of autologous fat and adipose derived stem cells (ADSCs) and introd...
متن کاملP47: Effects of Adipose Derived Stem Cells Transplantation on Locomotor Activity and Imbalance in Parkinson Model of Rats
Parkinson disease is a neurological disorder accompanied by degeneration of dopaminergic system and neuronal loss. Recently studies have focused on stem cells therapy, therefore the goal of this study was to investigate the effect of adipose derived stem cells grafting, on locomotion and imbalance in Parkinson model of rats. Twenty-four male Wistar rats weighing 200-250 g were divided into thre...
متن کامل